Horrifying Basal Cell Carcinoma Presenting as Progressive Pyoderma Gangrenosum: Case Report.

Case Rep Oncol

Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.

Published: February 2024

AI Article Synopsis

  • Skin ulcers can be difficult to diagnose, especially when they are related to other health issues like autoimmune and gastrointestinal diseases, and simple explanations might not always apply.
  • A case involving a 70-year-old male revealed that what was thought to be a skin condition related to Crohn's disease was actually basal cell carcinoma, which worsened and led to amputation.
  • The key takeaway is to always reassess a diagnosis and consider getting more expert opinions when a patient's condition doesn't improve, as earlier diagnosis could have prevented severe outcomes.

Article Abstract

Introduction: Skin ulcers can be challenging to diagnose and manage, particularly with comorbid autoimmune and gastrointestinal diseases. Occam's razor encourages the simplest explanation to guide care, but reconsideration must occur when intervention proves futile.

Case Presentation: We report the case of a 70-year-old male, with a 17-year history of expanding pretibial skin ulcer, presumed by prior care providers to be pyoderma gangrenosum related to Crohn's disease. A surgical biopsy performed upon presentation to our institution revealed basal cell carcinoma of the skin, invasive to the proximal tibia with associated deep infection, prompting transfemoral amputation.

Conclusion: This report is written as a reminder to reconsider a diagnosis and consider seeking additional expertise when a patient's condition progressively worsens despite intervention. Earlier diagnosis likely would have facilitated therapeutic limb salvage care.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10870126PMC
http://dx.doi.org/10.1159/000536445DOI Listing

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