Evaluation and comparison of antibacterial efficacy of different concentrations of Chhattisgarh herbal product- fruit extract in opposition to : An in vitro study.

Due to the low cost, natural origin, higher safety margins, and little to negligible adverse effects of herbal medications, the use of plants and plant derivatives in medicine is becoming increasingly widespread. is among the most significant medicinal plants in ayurvedic, siddha, unani, and homeopathic remedies. It is ranked first in Ayurvedic material medicine. has been shown to have established effects against various bacterial and fungal infections, including dental caries pathogens. In recent years, there has been a rise in interest in dentistry and medicine related to . The research aimed to assess the antibacterial effectiveness of different concentrations of ethanolic fruit extract (10%, 40%, and 100%) in opposition to and compare it with 2% chlorhexidine. For the study, ethanolic fruit extracts were obtained and prepared with Group I: -10% concentration, Group II: -40% concentration, Group III: -100% concentration, and Group IV: -2% chlorhexidine. Colonies of were cultivated in brain heart infusion (BHI) broth at 37°C and were inoculated in 16 BHI agar plates. Then, on the petri dishes, four wells were created (8 mm diameter) using a metal borer. The Agar well diffusion method was used to examine the antibacterial activity, and the zones of inhibition around the wells were noted. The obtained data were statistically analyzed using one-way ANOVA and post-hoc tests. The result shows that as the concentration increases, there is an increase in the efficacy of the antibacterial property of the extract before it reaches the saturation point. The decreasing order of antibacterial was chlorhexidine >100% >40% >10% . The production of contemporary pharmaceuticals from was addressed, as the global scenario is currently evolving toward using nontoxic plant products with traditional medicinal benefits.