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| http://dx.doi.org/10.1186/s12951-024-02327-5 | DOI Listing |
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Long-Term Performance and Safety of a Superficial HA Filler With Tri-Hyal Technology on Different Facial Zones: Forehead, Cheeks, Crow's Feet, and Upper Lips.
J Cosmet Dermatol
December 2024
Laboratoires FILL-MED, Paris, France.
Background: The function of injectable hyaluronic acid-based fillers is to smooth dermal wrinkles formed during aging. The aim of this study is to evaluate the performance and safety of a dermal filler after its commercialization.
Methods: In this context, an 18-month prospective randomized single-blind study for the efficacy and safety of ART FILLER Fine Lines (AFFL) was performed on the forehead, the upper lip, the cheek folds, and the crow's feet.
Correction: Ma et al. Hyaluronic Acid Modified Nanostructured Lipid Carrier for Targeting Delivery of Kaempferol to NSCLC: Preparation, Optimization, Characterization, and Performance Evaluation In Vitro. 2022, , 4553.
Molecules
December 2024
Department of Pharmacy, Mudanjiang Medical University, Mudanjiang 157000, China.
In the original publication [...
View Article and Find Full Text PDFSafety and Efficacy of Hydroxypropyl Guar-Hyaluronic Acid Dual-Polymer Lubricating Eye Drops in Indian Subjects with Dry Eye: A Phase IV Study.
Ophthalmol Ther
December 2024
The Eye Foundation, Coimbatore, Tamil Nadu, India.
Introduction: This work aimed to evaluate the safety and efficacy of hydroxypropyl guar-hyaluronic acid (HPG-HA) dual-polymer lubricating drops in Indian subjects with dry eye disease (DED).
Methods: This prospective, open-label, single-arm, phase IV study was conducted in India.
Inclusion Criteria: Adults (18-65 years) with an average total ocular surface staining (TOSS) score ≥ 4, best-corrected visual acuity of ≥ 20/40 in each eye, tear break-up time (TBUT) ≤ 10 s, and dry eye questionnaire (DEQ-5) score ≥ 6.
Comparison of facial profile attractiveness in pattern III patients treated with facial filling or orthognathic surgery.
J Craniomaxillofac Surg
November 2024
Department of Orthodontics, Ingá University Center UNINGÁ, Maringá, Brazil.
Objective: To compare facial profile attractiveness according to orthodontists, dentists, and laypeople in pattern III patients treated with facial filling or orthognathic surgery.
Materials And Methods: Thirty pattern III patients were retrospectively divided into two groups. Group 1 comprised 15 patients (10 females, five males; mean age 37.
Towards the goal of engineering of functional salivary gland tissues, we cultured primary human salivary stem/progenitor cells (hS/PCs) in hyaluronic acid-based matrices with varying percentages of proteolytically degradable crosslinks in the presence of Rho kinase (ROCK) inhibitor. Single cells encapsulated in the hydrogel grew into organized multicellular structures by day 15, and over 60% of the structures developed in the non-degradable and 50% degradable hydrogels contained a central lumen. Importantly, ROCK inhibition led to the establishment of multicellular structures that were correctly polarized, as evidenced by apical localization of a Golgi marker GM130, apical/lateral localization of tight junction protein zonula occludens-1 (ZO-1), and basal localization of integrin β1 and basement membrane proteins laminin α1 and collagen IV.
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