AI Article Synopsis
- Scientists are finding new drugs to help treat diseases like leishmaniasis and trypanosomiasis.
- Two researchers found a new drug that stops a part of the cells from working, which could be good for treating visceral leishmaniasis.
- This new drug might work even better when used with another drug called benznidazole for people with chronic Chagas' disease.
Article Abstract
The drug discovery pipeline for leishmaniasis and trypanosomiasis has been filling with novel chemical entities with known mechanisms of action. González et al. and Braillard et al. report a cytochrome bc complex inhibitor as another promising preclinical candidate for visceral leishmaniasis (VL) and, in combination with benznidazole, for chronic Chagas' disease (CCD).
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| http://dx.doi.org/10.1016/j.pt.2024.02.002 | DOI Listing |
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