AI Article Synopsis
- - Antisecretory medications, especially proton pump inhibitors (PPIs), help reduce gastrointestinal risks like upper gastrointestinal bleeding (UGIB) linked to NSAIDs and aspirin use, commonly taken in the U.S.
- - Health professionals recommend PPIs for patients who are at a high risk for UGIB due to their effectiveness in providing gastrointestinal protection.
- - The study investigates current trends in the prescribing of antisecretory medications for patients at high risk for UGIB, comparing this to prescribing patterns for patients with acid-related disorders.
Article Abstract
Antisecretory medications, primarily proton pump inhibitors (PPIs), have proven effective in reducing upper gastrointestinal toxicities, including upper gastrointestinal bleeding (UGIB), associated with nonsteroidal anti-inflammatory drugs (NSAIDs) and aspirin, which are among the most commonly used medications in the United States. Accordingly, professional guidance recommends PPIs for patients at high risk for UGIB. However, little is known about trends in use of antisecretory medications for gastrointestinal prophylaxis ("gastroprotection"). Herein, we examined contemporary use and prescribing of antisecretory medications in visits by patients at high risk for UGIB, relative to visits by patients diagnosed with acid-related disorders.
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| http://dx.doi.org/10.1016/j.cgh.2024.01.047 | DOI Listing |
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