AI Article Synopsis
- The cortex-like cytoskeleton is a crucial layer of proteins that affects how cell membranes behave and interact with their environment.
- Researchers are exploring the use of metal-phenolic networks to create these cytoskeletons in artificial cells made from liposomes.
- The resulting artificial cells show significant advantages like stability, resistance to harsh conditions, adjustable permeability, and controlled shapes, potentially paving the way for advanced applications in microsystems.
Article Abstract
Cortex-like cytoskeleton, a thin layer of cross-linked cytoplasmic proteins underlying the cell membrane, plays an essential role in modulating membrane behavior and cell surface properties. However, bottom-up construction of functional cortex-like cytoskeleton in artificial cells remains a challenge. Here, we present metal-phenolic networks as artificial cortical cytoskeletons in liposome-based artificial cells. The metal-phenolic cytoskeleton-reinforced artificial cells exhibit long-term stability, enhanced resistance to a variety of harsh environments, tunable permeability, and well-controlled morphologies. We anticipate that our stable artificial cell models will stride forward to practical applications of liposome-based microsystem.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10871533 | PMC |
| http://dx.doi.org/10.1126/sciadv.adj4047 | DOI Listing |
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