Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11092959 | PMC |
http://dx.doi.org/10.1164/rccm.202312-2274LE | DOI Listing |
J Clin Med
November 2024
Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany.
The intensity of respiratory treatment in acute respiratory distress syndrome (ARDS) is traditionally adjusted based on oxygenation severity, as defined by the mild, moderate, and severe Berlin classifications. However, ventilator-induced lung injury (VILI) is primarily determined by ventilator settings, namely tidal volume, respiratory rate, and positive end-expiratory pressure (PEEP). All these variables, along with respiratory elastance, are included in the concept of mechanical power.
View Article and Find Full Text PDFERJ Open Res
November 2024
National Heart and Lung Institute, Imperial College, London, UK.
Intensive Care Med Exp
October 2024
Department of Pathophysiology and Transplants, University of Milan, Milan, Italy.
Am J Respir Crit Care Med
May 2024
Royal Brompton Hospital, London, United Kingdom.
Crit Care
January 2024
Intensive Care Medicine Department, University Hospital of Heraklion, Heraklion, Crete, Greece.
Background: During control mechanical ventilation (CMV), the driving pressure of the respiratory system (ΔP) serves as a surrogate of transpulmonary driving pressure (ΔP). Expiratory muscle activity that decreases end-expiratory lung volume may impair the validity of ΔP to reflect ΔP. This prospective observational study in patients with acute respiratory distress syndrome (ARDS) ventilated with proportional assist ventilation (PAV+), aimed to investigate: (1) the prevalence of elevated ΔP, (2) the ΔP-ΔP relationship, and (3) whether dynamic transpulmonary pressure (Plung) and effort indices (transdiaphragmatic and respiratory muscle pressure swings) remain within safe limits.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!