Approach to difficult-to-treat asthma in childhood: a narrative review.

Singapore Med J

Department of Paediatrics, Respiratory Medicine Service, KK Women's and Children's Hospital, Singapore.

Published: February 2024

AI Article Synopsis

  • Asthma is a serious illness that affects many kids, and some kids have a harder time managing their asthma than others, which makes doctors spend a lot of time and money on their care.
  • Before treating asthma, doctors need to make sure it’s really asthma by doing tests and checking if other health issues like being overweight or smoking might be making things worse.
  • Treatment for tricky asthma can be personalized, meaning doctors find the best options for each patient, including using special medicines and tools, and sometimes using expensive treatments called biologics only if necessary.

Article Abstract

Asthma is a major chronic disease affecting children, and children with difficult-to-treat asthma account for a disproportionate share of resource utilisation and healthcare costs. This review presents a comprehensive and up-to-date overview of the treatment strategies in difficult-to-treat paediatric asthma. Mimickers of asthma must first be ruled out, and the diagnosis confirmed with objective tests whenever possible. The effect of comorbid conditions such as obesity, smoking, other atopic conditions and psychosocial factors on asthma control and severity should be considered. Treatment can then be optimised by implementing personalised strategies, including the use of appropriate drug delivery devices and adherence monitoring. Biologics can be an alternative treatment option for selected patients but should not be a substitute for addressing poor adherence. Many patients with difficult-to-treat asthma may not have severe asthma, and the physician should work with patients and families to achieve good asthma control via an individualised approach.

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Source
http://dx.doi.org/10.4103/singaporemedj.SMJ-2023-137DOI Listing

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