The deformability of blood vessels in one-dimensional blood flow models is typically described through a pressure-area relation, known as the tube law. The most used tube laws take into account the elastic and viscous components of the tension of the vessel wall. Accurately parametrizing the tube laws is vital for replicating pressure and flow wave propagation phenomena. Here, we present a novel mathematical-property-preserving approach for the estimation of the parameters of the elastic and viscoelastic tube laws. Our goal was to estimate the parameters by using ovine and human in vitro data, while constraining them to meet prescribed mathematical properties. Results show that both elastic and viscoelastic tube laws accurately describe experimental pressure-area data concerning both quantitative and qualitative aspects. Additionally, the viscoelastic tube law can provide a qualitative explanation for the observed hysteresis cycles. The two models were evaluated using two approaches: (i) allowing all parameters to freely vary within their respective ranges and (ii) fixing some of the parameters. The former approach was found to be the most suitable for reproducing pressure-area curves.
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http://dx.doi.org/10.1002/cnm.3803 | DOI Listing |
J Artif Organs
January 2025
Department of Human Environmental Science, Shonan Institute of Technology, 1-1-25 Tsujido-Nishi-Kaigan, Fujisawa, Kanagawa, 251-8511, Japan.
Abel JJ, Rowntree LG and Turner BB (Baltimore Trio) proposed the concept of vividiffusion and developed a vividiffusion apparatus in 1912. In a 1914 paper, they laid out the most important rule of device design. We named this rule an ART law taken from the initials of the Baltimore Trio.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
January 2025
Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Objective: Intestinal transplantation (ITx) has become an accepted option for children with serious complications from intestinal failure and parenteral nutrition (PN) dependence. We aimed to assess long-term growth and nutritional outcomes in these patients. We also assessed factors influencing nutritional status and ability to wean off tube feedings (TFs) after ITx.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Civil and Environmental Engineering, University of Florence, Via di S. Marta, 3, Florence, 50139, Italy.
Mathematical and physical modeling of flows in collapsible pipes often relates the flow area to the difference between the internal and the external pressures (i.e. the transmural pressure).
View Article and Find Full Text PDFAnalyst
January 2025
Wroclaw Medical University, Department of Forensic Medicine, 4 J. Mikulicza-Radeckiego Street, Wroclaw 50345, Poland.
JAMA
December 2024
Kidz First Neonatal Care, Te Whatu Ora Counties Manukau, Auckland, New Zealand.
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