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http://dx.doi.org/10.2142/biophysico.bppb-v20.s009 | DOI Listing |
Phys Chem Chem Phys
January 2025
Department of Applied Physics, Hebrew University, Jerusalem, Israel.
In an era of interdisciplinary scientific research, new methodologies are necessary to simultaneously advance several fields of study. One such case involves the measurement of electron spin effects on biological systems. While magnetic effects are well known in biology, recent years have shown a surge in published evidence isolating the dependence on spin, rather than magnetic field, in biological contexts.
View Article and Find Full Text PDFDokl Biol Sci
January 2025
Research Center of Neurology, Moscow, Russia.
Characteristic patterns of UV-induced skin autofluorescence were determined for patients with Parkinson's disease (PD) and associated with dysmetabolic alterations, such as nonenzymatic protein glycation, an increase in extracellular matrix stiffness, impaired metabolism of tissue fluorophores, mitochondrial dysfunction, and accumulation of aberrant proteins. Key differences in skin autofluorescence spectra were for the first time observed in PD, making it possible to discriminate between PD patients and healthy persons or individuals without signs of chronic neurodegeneration. Namely, skin fluorescence related to the reflected signal upon excitation with UV light at 375 nm was lower in PD patients.
View Article and Find Full Text PDFCell Biol Toxicol
January 2025
Department of Environmental Medicine, School of Medicine, Chongqing University, Chongqing, China.
Manganese (Mn) is a neurotoxin that has been etiologically linked to the development of neurodegenerative diseases in the case of overexposure. It is widely accepted that overexposure to Mn leads to manganism, which has clinical symptoms similar to Parkinson's disease (PD), and is referred to as parkinsonism. Astrocytes have been reported to scavenge and degrade extracellular α-synuclein (α-Syn) in the brain.
View Article and Find Full Text PDFAnal Methods
January 2025
Department of Chemistry, Capital Normal University, Beijing, 100048, China.
Catechins in tea, as promoters of human health, have attracted widespread attention. Herein, a dual-signal mode (colorimetric and fluorescence) sensor array for catechin species fingerprinting was built based on PtNi bunched nanoparticle (PtNi-BNP)--phenylenediamine (OPD)-HO system. PtNi-BNPs catalyze the reaction between OPD and HO to produce oxidized OPD (oxOPD) with both colorimetric (yellow) and fluorescent properties.
View Article and Find Full Text PDFReproduction
January 2025
Y Yu, Reproductive medical center, Peking University Third Hospital, Beijing, China.
In recent decades, it has become increasingly clear that mammalian gametes and early embryos are highly sensitive to metabolic substrates. With advances in single-cell sequencing, metabolomics, and bioinformatics, we now recognize that metabolic pathways not only meet cellular energy demands but also play a critical role in cell proliferation, differentiation, and fate determination. Investigating metabolic processes during oocyte maturation and early embryonic development is thus essential to advancing reproductive medicine and embryology.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!