Aims: Patients who have had anterior cruciate ligament reconstruction (ACL-R) should periodically have their muscle strength assessed. The five-times sit-to-stand test (FTSST) can evaluate the muscle strength and balance of the lower extremities. This study's primary purpose was to assess the validity and reliability of the FTSST in patients who have undergone ACL-R.
Material And Methods: Forty-three people who had undergone ACL-R surgery were included in the study. The study's primary outcome measure, the FTSST, was assessed by two different investigators. Secondary outcome measures were body balance, quadriceps muscle strength, Tegner activity score (TAS), and Lysholm score.
Results: The FTSST's test-retest and inter-rater reliability were both high (ICC: 0.99). The FTSST also showed a strong statistically significant correlation with all secondary outcome measures, including balance, quadriceps muscle strength, TAS, and Lysholm score (p<0.05).
Conclusions: According to the study results, the FTSST is a tool-free, simple method for assessing muscle strength and the body balance level, mobility level, and functional status of the knee in patients who have undergone ACL-R surgery.
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http://dx.doi.org/10.4314/mmj.v35i3.7 | DOI Listing |
Eur J Sport Sci
February 2025
Department of Sport and Health Sciences and Social Work, Oxford Brookes University, Oxford, UK.
Some technical limitations to using the eccentric mode to measure peak eccentric strength of the hamstrings (PTH) were raised. PTH also has limited validity to predict performance or injury risk factor. Therefore, our aim was to compare PTH and other isokinetic variables tested in the eccentric and passive modes.
View Article and Find Full Text PDFJ Cachexia Sarcopenia Muscle
February 2025
Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Background: With a decline of 17β-estradiol (E2) at menopause, E2 has been implicated in the accompanied loss of skeletal muscle mass and strength. We aimed at characterizing transcriptomic responses of skeletal muscle to E2 in female mice, testing the hypothesis that genes and pathways related to contraction and maintenance of mass are differentially expressed in ovariectomized mice with and without E2 treatment.
Methods: Soleus and tibialis anterior (TA) muscles from C57BL/6 ovariectomized mice treated with placebo (OVX) or E2 (OVX + E2) for 60 days, or from skeletal muscle-specific ERα knockout (skmERαKO) mice and wild-type littermates (skmERαWT), were used for genome-wide expression profiling, quantitative real-time PCR and immunoblotting.
J Cachexia Sarcopenia Muscle
February 2025
Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Background: Diaphragm thickness is a potential marker of sarcopenia in addition to muscle mass and strength at extremities. We aimed to clarify the descriptive epidemiology and prognostic significance of diaphragm thickness in the general population.
Methods: The study participants were 3324 community residents (mean age: 61.
Osteoarthritis Cartilage
January 2025
Department of Radiology and Biomedical Imaging, University of California, San Francisco.
Objective: Knee-adjacent subcutaneous fat (kaSCF) has emerged as a potential biomarker and risk factor for OA progression. This study aims to develop an AI-based tool for the automatic segmentation of kaSCF thickness and evaluate the cross-sectional associations between kaSCF, cartilage thickness, MRI-based cartilage T relaxation time, knee pain, and muscle strength independent of BMI.
Design: Baseline 3.
Clin Nutr ESPEN
January 2025
Coordinación de Nutrición Clínica, Departamento de Áreas Críticas, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico. Electronic address:
Background: Intensive care unit-acquired weakness (ICU-AW) is a complication characterized by decreased muscle mass and impairments in strength and physical function and is associated with poor quality of life and worse clinical outcomes. The primary objective of this study is to analyze the prevalence of ICU-AW, and secondary objectives were to assess risk factors and analyze the associations with clinical outcomes.
Methods: This is a prospective cohort study of patients on mechanical ventilation (MV).
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