AI Article Synopsis
- Pemphigoid vegetans is a rare form of bullous pemphigoid, with only 13 documented cases in medical literature.
- A case study involved a 63-year-old woman with painful lesions that progressed over four months, exhibiting specific histological features.
- The condition was diagnosed through histopathology and immunofluorescence, and it was effectively treated with oral corticosteroids, dapsone, and mycophenolate mofetil.
Article Abstract
Pemphigoid vegetans is a rare variant of bullous pemphigoid. Only 13 cases have been documented in the medical literature. The lesions clinically resemble pemphigus vegetans, but the histology is consistent with bullous pemphigoid. We present the case of a 63-year-old woman with painful vesicular and vegetative lesions progressing for 4 months. Histopathology showed a dermal-epidermal cleavage, epidermal acanthosis and an eosinophilic infiltrate. Direct immunofluorescence showed linear deposition of IgG and IgA at the junctional level. The diagnosis of pemphigoid vegetans was retained and successfully treated with oral corticosteroid, dapsone and mycophenolate mofetil.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10868469 | PMC |
| http://dx.doi.org/10.1177/2050313X241231535 | DOI Listing |
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