AI Article Synopsis
- The COVID-19 pandemic may contribute to delays in diagnosing serious illnesses like oral squamous cell carcinoma and worsen the management of patients with pre-existing health issues and oral lesions, including oral candidiasis, a common COVID-19 symptom.
- An 83-year-old female patient diagnosed with oral carcinoma developed oropharyngeal candidiasis after recovering from COVID-19 pneumonia, experiencing painful symptoms like difficulty swallowing and speaking.
- The study highlights a high risk of fungal infections in severe COVID-19 cases affecting the oral mucosa, though it's unclear if these infections are directly related to COVID-19 itself or other factors.
Article Abstract
Background And Purpose: The COVID-19 pandemic may be an aggravating risk factor for the delay of the diagnoses of serious illnesses, such as oral squamous cell carcinoma, as well as poor management of patients with underlying morbidities, the onset of oral lesions, and antifungal susceptibility to opportunistic fungal infections. Oral candidiasis is one of the most common oral features of COVID-19.
Case Report: This study aimed to report an 83-year-old female diagnosed with oral carcinoma who developed oropharyngeal candidiasis after falling ill with COVID-19. In late 2020, this patient was hospitalized for COVID-19 pneumonia. A fissured tongue with white scars appeared after the COVID-19 recovery that caused pain, dysphasia, and dysarthria. The sequencing result based on the internal transcribed spacer rDNA region confirmed . Its antifungal susceptibility showed susceptibility to nystatin, fluconazole, and caspofungin, but resistance to the other azoles and amphotericin B.
Conclusion: Risk of fungal infections, such as seems to be high in patients with severe COVID-19, mainly affecting the oral mucosa. However, whether they are directly attributed to COVID-19 or other surrounding factors is unknown.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864745 | PMC |
| http://dx.doi.org/10.22034/cmm.2023.345120.1478 | DOI Listing |
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