Fudging the volcano-plot without dredging the data.

Nat Commun

Univ. Grenoble Alpes, INSERM, CEA, UA13 BGE, CNRS, CEA, FR2048 ProFI, 38000, Grenoble, France.

Published: February 2024

Selecting omic biomarkers using both their effect size and their differential status significance (, selecting the “volcano-plot outer spray”) has long been equally biologically relevant and statistically troublesome. However, recent proposals are paving the way to resolving this dilemma.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869345PMC
http://dx.doi.org/10.1038/s41467-024-45834-7DOI Listing

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