Extended-spectrum β-lactamase-producing non-O1 was isolated from edible sp. in Vietnam. The genome sequence was sequenced using DNBSEQ-G400 and MinION Mk1b. A plasmid of approximately 183-kb encoding and was detected.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10927668PMC
http://dx.doi.org/10.1128/mra.01226-23DOI Listing

Publication Analysis

Top Keywords

inca/c plasmid
4
plasmid encoding
4
encoding non-o1
4
non-o1 isolates
4
isolates edible
4
edible river
4
river fish
4
fish extended-spectrum
4
extended-spectrum β-lactamase-producing
4
β-lactamase-producing non-o1
4

Similar Publications

This study aimed to explore the interactions among genetic determinants influencing ciprofloxacin resistance in . Treatment with PAβN, an efflux pump inhibitor, resulted in a 4-32-fold reduction in the minimum inhibitory concentration (MIC) across all 18 ciprofloxacin-resistant isolates. Notably, isolates without point mutations reverted from resistance to sensitivity.

View Article and Find Full Text PDF

The global spread of antimicrobial resistance genes (ARGs) poses a significant threat to public health. While antibiotics effectively treat bacterial infections, they can also induce gut dysbiosis, the severity of which varies depending on the specific antibiotic treatment used. However, it remains unclear how gut dysbiosis affects the mobility and dynamics of ARGs.

View Article and Find Full Text PDF
Article Synopsis
  • - E. coli ST8346 is a notable strain with multiple carbapenemases, identified in three isolates, which raises concerns about antibiotic resistance and transmission mechanisms.
  • - The study utilized various genetic and antibiotic testing methods to analyze the resistance profiles, revealing that all isolates were resistant to carbapenems and shared close genetic relationships despite lacking epidemiological connections.
  • - This research is the first to document the coexistence of these carbapenemases in E. coli ST8346, suggesting their spread comes from independent acquisition and highlighting the need for continued monitoring and research on antibiotic resistance.
View Article and Find Full Text PDF

The dissemination of multidrug-resistant and hypervirulent clones across the Kingdom of Saudi Arabia.

Emerg Microbes Infect

December 2024

Laboratory of Infectious Disease Epidemiology, KAUST Center of Excellence for Smart Health and Biological and Environmental Science and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia.

is a Gram-negative bacterium associated with a wide range of community- and hospital-acquired infections. The emergence of clonal hypervirulent strains resistant to last-resort antimicrobial agents has become a global concern. The Kingdom of Saudi Arabia (KSA), with its diverse population and high tourism traffic, serves as a platform where the spread of multidrug-resistant (MDR) strains are facilitated.

View Article and Find Full Text PDF
Article Synopsis
  • Acquired 16S rRNA methyltransferases (16S-RMTases) enable high resistance to aminoglycosides and are linked to resistance against other antibiotics like β-lactams and quinolones.
  • A study conducted on over 10,000 bacterial isolates from 2006 to 2023 found that 1.4% of them carried various methyltransferase genes alongside other significant resistance genes.
  • The research highlighted the diverse origins of these resistance genes in different plasmids and indicated that their ability to acquire more resistance genes poses a significant long-term public health risk.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!