AI Article Synopsis

  • A 1-year-old male and a 9-year-old female domestic shorthair cat were diagnosed with myasthenia gravis (MG) using various examinations including neurological assessments and blood tests.
  • The head tilt phenomenon (PHT) was observed in both cats at diagnosis, suggesting a neurological aspect of the condition.
  • The study proposes that the cause of PHT in cats with MG may be linked to muscle spindle dysfunction, similar to cases seen in hypokalaemic myopathy.

Article Abstract

Case Series Summary: A 1-year-old castrated male domestic shorthair cat was suspected with myasthenia gravis (MG) based on neurological examination, complete blood count (CBC), serum biochemistry, radiography and electrophysiological examination. In addition, a 9-year-old spayed female domestic shorthair cat was diagnosed with MG based on neurological examination, CBC, serum biochemistry, radiography, ultrasonography and increased acetylcholine receptor antibody titre. Positioning head tilt (PHT) was observed at the time of diagnosis in both cats.

Relevance And Novel Information: Although the pathophysiology of PHT in cats is not fully understood, the mechanism for PHT in cats with MG may be similar to that of cats with hypokalaemic myopathy, supporting our hypothesis that muscle spindle dysfunction causes PHT.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10865950PMC
http://dx.doi.org/10.1177/20551169231224534DOI Listing

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