Restless legs syndrome in chronic renal failure patients on dialysis.

Afr Health Sci

Department of Neurology, School of Clinical Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Published: September 2023

AI Article Synopsis

  • The study investigated the prevalence and impact of restless legs syndrome (RLS) among 100 dialysis patients with chronic renal failure.
  • Six patients met the international criteria for RLS, while 24 reported symptoms suggestive of it, indicating that RLS affected 30% of the cohort.
  • Patients with RLS symptoms experienced more sleep disturbances and other complications, highlighting the importance of early identification and intervention for RLS in this population.

Article Abstract

Background: Restless legs syndrome (RLS) occurs in patients with chronic renal failure (CRF).

Objectives: To determine the prevalence and morbidity of RLS in CRF patients on dialysis.

Methods: This cross-sectional questionnaire-based study included 100 dialysis patients (50 on haemodialysis [HD]; 50 on peritoneal dialysis [PD]). A focused lower limb examination was done. Patients were classified with RLS when reporting uncomfortable feelings in their legs that improved with movement and worsened when resting and at night.

Results: Gender distribution was equal. The median age was 43 (19-67) years. Six patients (HD and PD n=3 each) had international criteria-confirmed RLS. Twenty-four patients reported symptoms suggestive of RLS. Fourteen and 16 patients with RLS symptoms were on HD and PD, respectively. Sleep disturbances occurred in 43.3% (n=13) of patients with RLS symptoms, compared to 20.0% (n=20) of the large cohort. Sleep disturbances, peripheral sensory loss, chronic disease-related anaemia, increased urea and decreased albumin levels were more common among patients with RLS symptoms.

Conclusion: RLS symptoms occurred in 30.0% of the entire cohort, although only 6.0% met the international criteria. The type of dialysis had no impact on the incidence of symptoms. Identifying RLS in patients with CRF on dialysis will allow for early intervention.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10862641PMC
http://dx.doi.org/10.4314/ahs.v23i3.88DOI Listing

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