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5-Year Results From the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial.
J Am Coll Cardiol
November 2024
University Hospital of Bern, Bern, Switzerland.
Background: The Amulet IDE trial (AMPLATZER Amulet Left Atrial Appendage Occluder [LAAO] Investigational Device Exemption [IDE] Trial) evaluated the safety and effectiveness of the Amulet occluder (Abbott) in patients with nonvalvular atrial fibrillation. The Amulet IDE trial is the largest randomized LAAO trial, comparing the Amulet occluder with the Watchman 2.5 device (Boston Scientific).
View Article and Find Full Text PDFPulmonary Artery Injury Following Endocardial Left Atrial Appendage Occlusion: The Known and Unknown.
JACC Clin Electrophysiol
December 2024
Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA. Electronic address:
Article Synopsis
- Left atrial appendage closure (LAAC) is used as an alternative stroke prevention method for patients who cannot take blood thinners, but pulmonary artery injury (PAI) is a rare and serious complication associated with it.
- A review of previous PAI cases and data from the FDA's MAUDE database identified 36 cases, predominantly involving older patients, and highlighted that PAI often presents soon after the procedure, with a significant percentage requiring surgery.
- The study emphasizes the need for heightened awareness of PAI symptoms post-LAAC, especially concerning rapid fluid accumulation around the heart, even without clear predictive signs from imaging or clinical details.
Clinical outcome and intraprocedural characteristics of left atrial appendage occlusion: a comparison between single-occlusive plug-type and dual-occlusive disc-type devices.
Front Cardiovasc Med
July 2024
Deutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany.
Article Synopsis
- Percutaneous interventional left atrial appendage occlusion (LAAO) is a proven method for preventing strokes in patients with atrial fibrillation (AF) and has been evaluated in a study involving 149 patients at a Berlin hospital from 2016 to 2022.
- The study compared two types of devices used in LAAO: single-occlusive plug-type (SOPT) and dual-occlusive disc-type (DODT), noting that while DODT procedures took longer, both had successful implantation with low rates of complications and no hospital deaths.
- After six months, findings indicated that SOPT had a higher rate of device-related thrombus formation compared
Interventional closure of an iatrogenic LAA-perforation by means of a PFO-occluder.
Catheter Cardiovasc Interv
October 2024
Medical Clinic II, University Heart Center Lübeck, University Hospital Schleswig-Holstein, Lübeck, Germany.
Article Synopsis
- * An 87-year-old patient undergoing elective LAA closure experienced a rare but serious complication—pericardial effusion—leading to cardiac arrest, which required CPR.
- * The complication was resolved by sealing the perforation with a PFO-occluder, demonstrating that serious issues during procedures can sometimes be treated with interventional techniques, avoiding more invasive surgeries.
[A complicated left atrial appendage closure : percutaneous management of LAA rupture].
Ann Cardiol Angeiol (Paris)
September 2024
Département de Cardiologie, Institut Mutualiste Montsouris, Paris, France.
An 81-year-old patient was referred for left atrial appendage closure. Anatomical LAA analysis by CT scan showed an inverted chicken wing morphology. The procedure was performed through i an infero-anterior transseptal puncture and led to "sandwich" closure strategy using an AMPLATZER AMULET 25 mm device.
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