Disease-associated microglia (DAMs) are a unique microglial state in development and various CNS pathologies. In this issue of Immunity, Lan and colleagues provide novel insights into the diversity of DAMs in CNS diseases, revealing their terminal fate following juvenile stroke verses their reversible fate following neonatal stroke and their ability to maintain immune memory upon return to homeostatic states.
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| http://dx.doi.org/10.1016/j.immuni.2024.01.004 | DOI Listing |
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