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Ultra-processed food intake and prevalence of osteoporosis in US adults aged 50 years and older: a cross-sectional analysis.
Osteoporos Int
January 2025
Rush Biostatistics and Bioinformatics Core, Rush University, 600 S. Paulina St., Chicago, IL, 60612, USA.
Unlabelled: Dietary quality may be a factor in the progression of non-communicable, chronic diseases. This analysis of NHANES data demonstrates association between consumption of UPF and prevalence of osteoporosis and osteopenia in adults 50 years and older. UPF intake is an important consideration when recommending dietary patterns for optimum bone health PURPOSE: Declining bone mineral density in older adults can result in osteoporosis, leading to decreased physical function, quality of life, and increased risk of mortality.
View Article and Find Full Text PDF'Bone Health-Across a Woman's Lifespan'.
Clin Endocrinol (Oxf)
January 2025
Centre for Endocrinology & Metabolism, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Despite a high burden of osteoporosis and minimal trauma fractures worldwide, there is still a treatment gap in timely diagnosis and optimal treatment. There is also a lack of international consensus and guidelines on the management of bone fragility in premenopausal women. This review article provides an overview of the current understanding of factors impacting women's bone health across the adult lifespan, as well as dilemmas in the diagnosis, assessment and management of osteoporosis in premenopausal and postmenopausal women, premature ovarian insufficiency and bone health following breast cancer.
View Article and Find Full Text PDFThe absence of IRG1 exacerbates bone loss in a mouse model of ovariectomy-induced osteoporosis by increasing osteoclastogenesis through the potentiation of NLRP3 inflammasome activation.
Int Immunopharmacol
January 2025
Department of Endocrinology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 610072, China. Electronic address:
The immune-responsive gene 1 (IRG1) protein plays a role in various pathological processes by connecting cellular metabolism to a range of cellular activities through the production of itaconate. Recent studies have highlighted the significance of IRG1 and itaconate in bone metabolism and homeostasis. However, the precise role of IRG1 in osteoporosis remains inadequately documented.
View Article and Find Full Text PDFAlendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women.
Cochrane Database Syst Rev
January 2025
Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Rationale: Osteoporosis is an abnormal reduction in bone mass and bone deterioration, leading to increased fracture risk. Alendronate belongs to the bisphosphonate class of drugs, which inhibit bone resorption by interfering with the activity of osteoclasts (bone cells that break down bone tissue). This is an update of a Cochrane review first published in 2008.
View Article and Find Full Text PDFAssociation Between Allometric Body Shape Indices and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study from NHANES.
Int J Womens Health
January 2025
Department of Endocrinology, The First People's Hospital of Xiaoshan District, Hangzhou, Zhejiang, People's Republic of China.
Background: Osteoporosis is a common health concern in postmenopausal women. Obesity, commonly assessed using body mass index (BMI), may have a protective effect on osteoporosis in postmenopausal women. As BMI is limited to the distinguishing fat accumulation, the study aimed to explore the association between allometric body shape indices [including a body shape index (ABSI), hip index, (HI), and waist-hip index (WHI)] and osteoporosis in postmenopausal women.
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