Idiopathic terminal ileitis: myth or true entity?

Curr Opin Gastroenterol

Academic Unit of Gastroenterology and Hepatology, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, UK.

Published: May 2024

Purpose Of Review: Isolated terminal ileitis is an increasing phenomenon identified during colonoscopy. Idiopathic terminal ileitis (IDTI) is a diagnosis of exclusion, representing a significant challenge from a diagnostic and management point of view. This review provides an overview of the most recent and relevant evidence on idiopathic IDTI, focusing on its evolution, the natural history and the management strategies proposed in the literature.

Recent Findings: IDTI is uncommon, with a reported prevalence between 0.5 and 7%. The main differential is with Crohn's disease and intestinal tuberculosis in endemic countries. A proportion of patients (0-50%) can progress and develop Crohn's disease; however, there are no reliable predictive factors to stratify IDTI patients.

Summary: IDTI is a challenging entity, with a small proportion of patients progressing to Crohn's disease over time thus requiring follow-up. Noninvasive modalities such as capsule endoscopy are useful for follow-up, but further research is required to better understand this entity.

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOG.0000000000001011DOI Listing

Publication Analysis

Top Keywords

terminal ileitis
12
crohn's disease
12
idiopathic terminal
8
proportion patients
8
idti
5
ileitis myth
4
myth true
4
true entity?
4
entity? purpose
4
purpose review
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!