AI Article Synopsis
- This study aimed to assess how common group B Streptococcus (GBS) is among pregnant women and their newborns, as well as the risk of passing it from mother to child.
- Researchers analyzed 54 studies involving nearly 356,000 women and infants from 30 countries, finding a GBS colonization rate of 17.1% in pregnant women and 1.0% in newborns, with a 4.5% rate of vertical transmission.
- The study recommends giving antibiotics during labor to all women who test positive for GBS and those at risk of transmitting it to their infants, regardless of their GBS status.
Article Abstract
Aim: To determine the prevalence of group B Streptococcus (GBS) carriage among parturient women and neonates, and the relative risk of vertical transmission, the relative risk of early and late-onset GBS and the pooled incidence of early-late-onset GBS infection.
Methods: A systematic search of relevant cohort studies from three electronic databases to identify all relevant studies published up to 7 November 2022. The review was conducted in accordance with PRISMA guidelines. Estimates were pooled using random-effects meta-analyses.
Results: A total of 54 articles with 355 787 matched pairs of parturient women and neonates from 30 countries were included in the analysis. The pooled prevalence of GBS colonisation was 17.1% among the pregnant women and 1.0% among neonates. The pooled prevalence of vertical transmission of GBS was 4.5% and the pooled relative risk of GBS colonisation of neonates born to mothers with GBS was 9.9.
Conclusion: We support the implementation of targeted intrapartum antibiotic prophylaxis for all women who are positive for GBS as well as women with risks factors for early onset GBS in their infants regardless of their GBS colonisation status.
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| http://dx.doi.org/10.1111/apa.17152 | DOI Listing |
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