AI Article Synopsis
- * Skin biopsies confirmed both nephrogenic systemic fibrosis and calciphylaxis, despite the patient never having been exposed to gadolinium-based contrast agents.
- * Despite receiving treatment that included daily dialysis and sodium thiosulfate, he rapidly deteriorated and passed away within two weeks due to complications from hospital-acquired pneumonia.
Article Abstract
We present a case of a man in his 40s who was on haemodialysis for over 20 years presenting with rapidly progressive decline in mobility, associated with fixed flexion deformities of joints and peau d'orange appearance of skin together with areas of ulceration that was concerning for calciphylaxis. Skin biopsies were consistent with both nephrogenic systemic fibrosis and calciphylaxis. He has never had exposure to gadolinium-based contrast agent. His treatment included daily dialysis sessions, which were challenging due to vascular access issues and three times weekly sodium thiosulfate. He rapidly declined in hospital and died within 2 weeks of presentation while being treated for a hospital-acquired pneumonia.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10868240 | PMC |
| http://dx.doi.org/10.1136/bcr-2023-258482 | DOI Listing |
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