Cancer patients are known to have a higher likelihood of developing Cardiovascular Disease (CVD) compared to non-cancer individuals. Although various types of cancer can contribute to the onset of CVD, lung cancer is inherently linked with increased susceptibility. To bridge this hypothesis, we propose a Lung cancer detection and Cardiovascular Disease Prediction (LCDP) system through lung Computed Tomography (CT) scan images. The lung cancer detection module of the LCDP system utilizes Transfer Learning (TL) with AdaDenseNet for classification. It employs the improvised Proximity-based Synthetic Minority Over-sampling Technique (Prox-SMOTE), improving accuracy. In the CVD prediction module, the feature extraction was performed using the VGG-16 model, followed by classification using a Support Vector Machine (SVM) classifier. The impact and interdependence of lung cancer on CVD were evident in our evaluation, with high accuracies of 98.28% for lung cancer detection and 91.62% for CVD prediction.
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http://dx.doi.org/10.1109/JBHI.2024.3365176 | DOI Listing |
JACS Au
December 2024
Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Four new macrolides, spirosnuolides A-D (-, respectively), were discovered from the termite nest-derived sp. INHA29. Spirosnuolides A-D are 18-membered macrolides sharing an embedded [6,6]-spiroketal functionality inside the macrocycle and are conjugated with structurally uncommon side chains featuring cyclopentenone, 1,4-benzoquinone, hydroxyfuroic acid, or butenolide moieties.
View Article and Find Full Text PDFIndian J Orthop
January 2025
Department of Orthopedics and Traumatology, Abdurrahman Yurtaslan Training and Research Hospital, Ankara, Turkey.
Background: Soft-tissue sarcoma involving the popliteal fossa remains challenging because it is difficult to achieve wide margins with limb salvage in this location. Adjuvant therapy is frequently necessary, and limb function can be adversely affected. We reviewed our experience with these tumors.
View Article and Find Full Text PDFIran J Parasitol
January 2024
Department of Chest Diseases, School of Medicine, Hacettepe University, Ankara, Turkey.
remains a global public health issue. Although predominantly affecting the liver, the lungs are the second most affected organ and often undergo surgical intervention. Here, a case managed by bronchoscopy and medical therapy is presented.
View Article and Find Full Text PDFFront Public Health
December 2024
School of Preventive Medicine, Shandong First Medical University (Institute of Radiation Medicine, Shandong Academy of Medical Sciences), Jinan, Shandong, China.
Background: Radon, a colorless and odorless radioactive gas, poses serious health risks. It is the second leading cause of lung cancer and notably increases lung cancer risk in smokers. Although previous epidemiological studies have mainly examined lung cancer rates in miners, the effects of radon on genomic stability and its molecular mechanisms are not well understood.
View Article and Find Full Text PDFOncol Res
December 2024
Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Background: Aberrant expression of RNA-binding proteins (RBPs) has been linked to a variety of diseases, including hematological disorders, cardiovascular diseases, and multiple types of cancer. Heterogeneous nuclear ribonucleoprotein C (HNRNPC), a member belonging to the heterogeneous nuclear ribonucleoprotein (hnRNP) family, plays a pivotal role in nucleic acid metabolism. Previous studies have underscored the significance of HNRNPC in tumorigenesis; however, its specific role in malignant tumor progression remains inadequately characterized.
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