The article analyzes past history, main milestones of making, research and improvement of anatoxins from works of Gaston Ramon who first proposed 100 years ago method of obtaining reliable vaccine preparation (anatoxin) on the basis of formalin neutralized diphtheria (and then tetanus) toxin (1922-1923) to nowadays scientific achievements in prevention and treatment of these infectious diseases.
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[Setting up a training program in a geriatric short-stay department].
Soins Gerontol
June 2024
Centre hospitalier Gaston-Ramon, 89100 Sens, France.
As the department's team had been renewed in less than two years, it was necessary to invent a method to improve cohesion and communication, and to enhance the skills of professionals. This led to the creation of a training program using a variety of methods (theoretical training, care approaches and quality coffees).
View Article and Find Full Text PDFLevodopa-Induced Dyskinesias are Frequent and Impact Quality of Life in Parkinson's Disease: A 5-Year Follow-Up Study.
Mov Disord Clin Pract
July 2024
Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
Background: Levodopa-induced dyskinesias (LID) are frequent in Parkinson's disease (PD).
Objective: To analyze the change in the frequency of LID over time, identify LID related factors, and characterize how LID impact on patients' quality of life (QoL).
Patients And Methods: PD patients from the 5-year follow-up COPPADIS cohort were included.
[Gaston Ramon and concise history of anatoxins (to the centenary of discovery)].
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med
January 2024
The Federal State Autonomous Educational Institution of Higher Education "The Patrice Lumumba Peoples' Friendship University" of Russia of Minobrnauka of Russia (RUDN University), 117198, Moscow, Russia.
The article analyzes past history, main milestones of making, research and improvement of anatoxins from works of Gaston Ramon who first proposed 100 years ago method of obtaining reliable vaccine preparation (anatoxin) on the basis of formalin neutralized diphtheria (and then tetanus) toxin (1922-1923) to nowadays scientific achievements in prevention and treatment of these infectious diseases.
View Article and Find Full Text PDFGaston Ramon's Big Four.
Toxins (Basel)
January 2024
MERIT, Institut de Recherche pour le Développement, Université Paris Cité, F-75006 Paris, France.
Article Synopsis
- Gaston Ramon was a pioneering figure in the early development of humoral immunology during a time when the field was just beginning to emerge.
- He made significant contributions that advanced the understanding of immune responses and the role of antibodies.
- His work laid the groundwork for future research and developments in immunology, shaping how we understand immune systems today.
Staging Parkinson's disease according to the MNCD classification correlates with caregiver burden.
Brain Behav
December 2023
Department of Neurology, Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
Background And Objective: Recently, we demonstrated that staging Parkinson's disease (PD) with a novel simple classification called MNCD, based on four axes (motor, non-motor, cognition, and dependency) and five stages, correlated with disease severity and patients' quality of life. Here, we analyzed the correlation of MNCD staging with PD caregiver's status.
Patients And Methods: Data from the baseline visit of PD patients and their principal caregiver recruited from 35 centers in Spain from the COPPADIS cohort from January 2016 to November 2017 were used to apply the MNCD total score (from 0 to 12) and MNCD stages (from 1 to 5) in this cross-sectional analysis.
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