The article considers organizational issues of cervical cancer screening in the Russian Federation. In particular, experience of implementation of the Project "HPV testing within the framework of combined cervical cancer screening (HPV and cytologic screening) in the Republic of Bashkortostan is considered. The cervical cancer is a widespread disease that requires early diagnosis and timely medical care. The main aspects of organization of medical care of patients with gynecological diseases in relevant normative legal regulatory documents are described. The algorithm and scheme of routing patients with suspected cervical cancer and with this disease are presented. The study covered more than 60,000 women aged 30-39 years from 14 medical organizations of Ufa. Such methods as sociological, statistical, analytical, content-analysis and organizational experiment were applied. The study permitted to substantiate and to approve both the Project "HPV testing as part of combined screening for cervical cancer (HPV screening and cytologic screening) and the algorithm of combined screening of cervical cancer during preventive examinations of female adult population aged 30-39 years of the Republic of Bashkortostan. The scheme was developed for routing patients with suspected cervical cancer or diagnosed disease to medical organizations for timely medical care support. By implementing developed routing and screening scheme for patients at risk of developing cervical cancer, as well as those who already suffer this pathology, it is possible to improve quality of organization and delivery of medical care, to reduce morbidity, mortality and disability because of this pathology and to assure early diagnosis and prevention of cervical cancer.

Download full-text PDF

Source
http://dx.doi.org/10.32687/0869-866X-2024-32-1-75-82DOI Listing

Publication Analysis

Top Keywords

cervical cancer
36
medical care
16
combined screening
12
cancer
10
screening
9
cervical
9
cancer screening
8
project "hpv
8
"hpv testing
8
cytologic screening
8

Similar Publications

Early cancer detection substantially improves the rate of patient survival; however, conventional screening methods are directed at single anatomical sites and focus primarily on a limited number of cancers, such as gastric, colorectal, lung, breast, and cervical cancer. Additionally, several cancers are inadequately screened, hindering early detection of 45.5% cases.

View Article and Find Full Text PDF

Objective: Cervical cancer is a common malignancy among women, and radiotherapy remains a primary treatment modality across all disease stages. However, resistance to radiotherapy frequently results in treatment failure, highlighting the need to identify novel therapeutic targets to improve clinical outcomes.

Methods: The expression of molecule interacting with CasL-2 (MICAL2) was confirmed in cervical cancer tissues and cell lines through western blotting (WB) and immunohistochemistry (IHC).

View Article and Find Full Text PDF

Introduction: Existing evidence suggests a lower uptake of cervical cancer screening among Indian women. Coverage is lower in rural than urban women, but such disparities are less explored. So, the present study was conducted to explore the self-reported coverage of cervical cancer screening in urban and rural areas stratified by socio-demographic characteristics, determine the spatial patterns and identify any regional variations, ascertain the factors contributing to urban-rural disparities and those influencing the likelihood of screening among women aged 30-49 years factors residing in urban, rural, and overall Indian settings.

View Article and Find Full Text PDF
Article Synopsis
  • Cervical cancer is the fourth most common cancer in women globally, and this study introduces a deep learning framework to predict molecular subtypes in HPV-positive cervical squamous cell carcinoma using histology slides.
  • The research analyzed three cohorts with 545 patients, demonstrating that the Digital-CMS scores can effectively predict both disease-specific and disease-free survival outcomes.
  • Furthermore, the study found significant differences in the tumor microenvironment between subtypes, highlighting potential biomarkers and therapeutic targets that could guide clinical applications for better patient management.
View Article and Find Full Text PDF

Cervical cancer continues to disproportionately burden women in sub-Saharan Africa, and is the commonest gynecological cancer in Ghana. The Cervical Cancer Prevention and Training Centre (CCPTC), Battor, Ghana spearheaded the Ghana arm of the mPharma 10,000 Women Initiative (mTTWI) between September 2021 and October 2022. The aim of this study was to examine the outcomes of nationwide concurrent screening using high-risk human papillomavirus (hr-HPV) DNA testing and visual inspection methods, as well as factors associated with the screening outcomes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!