AI Article Synopsis

  • Crocodile tear syndrome (CTS) occurs after facial nerve palsy and leads to tears when eating, affecting only one side of the face.
  • Two patients who had CTS after recovering from idiopathic facial nerve palsy received injections of incobotulinumtoxinA into the lacrimal gland.
  • After treatment, both patients saw improvement, with the one receiving a higher dose experiencing temporary side effects like droopy eyelid and double vision, while the other had no adverse effects.

Article Abstract

Crocodile tear syndrome (CTS) is a late complication of facial nerve palsy characterized by unilateral lacrimation in response to gustatory stimulation. We present 2 cases of patients diagnosed with CTS after recovering from unilateral idiopathic facial nerve palsy. Both patients underwent transconjunctival lacrimal gland incobotulinumtoxinA injection, with doses of 5-16 units. The patients were seen in clinic for post-treatment follow-up at 2 weeks, 3 months, and 6 months. Outcomes were measured by treatment efficacy and adverse drug effects. Following treatment, both patients reported resolution of gustatory lacrimation. The patient treated with 16 U experienced transient ptosis and diplopia following injection, whereas the patient treated with 5-7.5 U experienced no adverse effects.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10854408PMC
http://dx.doi.org/10.5693/djo.02.2023.09.001DOI Listing

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Article Synopsis
  • Crocodile tear syndrome (CTS) occurs after facial nerve palsy and leads to tears when eating, affecting only one side of the face.
  • Two patients who had CTS after recovering from idiopathic facial nerve palsy received injections of incobotulinumtoxinA into the lacrimal gland.
  • After treatment, both patients saw improvement, with the one receiving a higher dose experiencing temporary side effects like droopy eyelid and double vision, while the other had no adverse effects.
View Article and Find Full Text PDF

The purpose of this review was to study the evaluation, diagnosis, and management of ophthalmic complications associated with facial nerve palsy and to discuss the current and future interventions. The ophthalmic complications of facial paralysis include lagophthalmos, ectropion, exposure keratopathy, ocular synkinesis, and crocodile tears. Evaluation by an ophthalmologist skilled in recognizing and managing complications of facial paralysis shortly after its initial diagnosis can help identify and prevent long-term complications.

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Crocodile tears syndrome after vestibular schwannoma surgery: A case report.

Int J Surg Case Rep

October 2023

Department of Neurosurgery, Seth G.S. Medical College and King Edward Memorial Hospital, Acharya Dhonde Marg, Parel, Mumbai 400012, Maharashtra, India.

Introduction: Crocodile tears syndrome is paroxysmal lacrimal hypersecretion while eating or drinking. It is relatively rare and mainly observed after peripheral facial nerve injury due to any cause.

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