Road pavement monitoring represents the starting point for the pavement maintenance process. To quickly fix a damaged road, relevant authorities need a high-efficiency methodology that allows them to obtain data describing the current conditions of a road network. In urban areas, large-scale monitoring campaigns may be more expensive and not fast enough to describe how pavement degradation has evolved over time. Furthermore, at low speeds, many technologies are inadequate for monitoring the streets. In such a context, employing black-box-equipped vehicles to perform a routine inspection could be an excellent starting point. However, the vibration-based methodologies used to detect road anomalies are strongly affected by the speed of the monitoring vehicles. This study uses a statistical method to analyze the effects of speed on road pavement conditions at different severity levels, through data recorded by taxi vehicles. Likewise, the study introduces a process to overcome the speed effect in the measurements. The process relies on a machine learning approach to define the decision boundaries to predict the severity level of the road surface condition based on two recorded parameters only: speed and pavement deterioration index. The methodology has succeeded in predicting the correct damage severity level in more than 80% of the dataset, through a user-friendly real-time method.
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http://dx.doi.org/10.3390/s24030925 | DOI Listing |
Nat Commun
December 2024
Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Institutes of Respiratory Diseases, School of Medicine, Shanghai Jiao Tong University and Shanghai Key Laboratory of Emergency Prevention, Diagnosis and Treatment of Respiratory Infectious Diseases, Shanghai, China.
Human adenovirus (HAdV) is a widely spread respiratory pathogen that can cause infections in multiple tissues and organs. Previous studies have established an association between HAdV species B (HAdV-B) infection and severe community-acquired pneumonia (SCAP). However, the connection between SCAP-associated HAdV-B infection and host factor expression profile in patients has not been systematically investigated.
View Article and Find Full Text PDFNat Commun
December 2024
Imperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Lactobacillus species dominance of the vaginal microbiome is a hallmark of vaginal health. Pathogen displacement of vaginal lactobacilli drives innate immune activation and mucosal barrier disruption, increasing the risks of STI acquisition and, in pregnancy, of preterm birth. We describe differential TLR mediated activation of the proinflammatory transcription factor NF-κB by vaginal pathogens and commensals.
View Article and Find Full Text PDFSmall
December 2024
Department of Electrical and Electronic Engineering, Engineering Building A, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Plasmonic catalysis, whereby either an optically resonating metal couples to a catalytic material or a catalytic metal particle achieves optical resonance, has been a mainstay of photo-catalysis research for the past few decades. However, a new field of metal-dielectric metamaterials, including plasmonic metamaterials, is emerging as the next frontier in catalysis research. With new optical behaviors that can be achieved by sub-wavelength structures, in either periodic or semi-periodic arrangements, metamaterials can overcome some of the limitations of conventional plasmonic catalysis.
View Article and Find Full Text PDFCytotechnology
February 2025
College of Veterinary Medicine, Qingdao Agricultural University, No. 700 Changcheng Road, Chengyang, Qingdao, 266109 China.
Osteoarthritis is a degenerative disease of cartilage, and exosome derived from mesenchymal stem cells (MSCs) are considered promising for treating inflammatory musculoskeletal disorders, although their mechanisms are not fully understood. This study aimed to investigate the effects of exosomes derived from canine bone marrow mesenchymal stem cells (cBMSCs-Exos) on the expression of inflammatory factors and genes related cartilage matrix metabolism in IL-1β-induced canine chondrocytes. Canine BMSCs were isolated and characterized for surface markers and trilineage differentiation.
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