AI Article Synopsis
- - Respiratory syncytial virus (RSV) is a major cause of respiratory infections, particularly affecting infants, the elderly, and those with weakened immune systems, leading to significant economic impacts globally.
- - Recent studies have focused on RSV's molecular structure and functions, resulting in advancements in treatments that target different stages of its replication cycle, such as fusion and polymerase inhibitors.
- - With the approval of prophylactic drugs like palivizumab and nirsevimab by the FDA, researchers are optimistic that these findings will facilitate further knowledge and inspire new research initiatives.
Article Abstract
Respiratory syncytial virus (RSV) is a significant viral pathogen that causes respiratory infections in infants, the elderly, and immunocompromised individuals. RSV-related illnesses impose a substantial economic burden worldwide annually. The molecular structure, function, and in vivo interaction mechanisms of RSV have received more comprehensive attention in recent times, and significant progress has been made in developing inhibitors targeting various stages of the RSV replication cycle. These include fusion inhibitors, RSV polymerase inhibitors, and nucleoprotein inhibitors, as well as FDA-approved RSV prophylactic drugs palivizumab and nirsevimab. The research community is hopeful that these developments might provide easier access to knowledge and might spark new ideas for research programs.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10856762 | PMC |
| http://dx.doi.org/10.3390/molecules29030598 | DOI Listing |
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