Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.chest.2023.09.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Standardizing postoperative pain control for decompression of pediatric Chiari type I malformation by limiting narcotic usage.
J Neurosurg Pediatr
January 2025
2Division of Pediatric Neurosurgery, Johns Hopkins All Children's Hospital, St. Petersburg, Florida.
Objective: The aim of this study was to assess the effectiveness of a postoperative multimodal pain control protocol on perioperative pain scores in children undergoing decompression for Chiari type I malformation (CM-I).
Methods: This retrospective matched cohort study included patients < 21 years of age who underwent elective suboccipital craniectomy and C1 laminectomy for CM-I with or without duraplasty at a single center from January 2020 to July 2023. A standardized, multimodal postoperative pain protocol was implemented in August 2021 that did not use narcotic patient-controlled analgesia.
Developments and clinical experiences in collagenase chemonucleolysis for lumbar disc herniation: a narrative review.
Front Med (Lausanne)
January 2025
Department of Orthopedic, Dianjiang People's Hospital of Chongqing, Chongqing, China.
Lumbar disc herniation (LDH) affects millions globally, with annual healthcare costs exceeding $100 billion in the United States alone, driving increasing interest in minimally invasive radiological interventions as treatment alternatives. This narrative review examines developments in collagenase chemonucleolysis for LDH, integrating a literature analysis with clinical experience. Key advancements include the transition from single-agent to combination therapies, exploration of diverse injection routes, and the progression from C-arm fluoroscopy to multi-slice CT guidance.
View Article and Find Full Text PDFElectrospun robust, biodegradable, bioactive, and nanostructured sutures to accelerate the chronic wound healing.
Biofabrication
January 2025
College of Textiles & Clothing, Qingdao University, 308 Ningxia Road, Qingdao, Qingdao, Shandong, 266071, CHINA.
The design and development of advanced surgical sutures with appropriate structure and abundant bio-functions are urgently required for the chronic wound closure and treatment. In this study, an integrated technique routine combining modified electrospinning with hot stretching process was proposed and implemented to fabricate poly(L-lactic acid) (PLLA) nanofiber sutures, and the Salvia miltiorrhiza Bunge-Radix Puerariae herbal compound (SRHC) was encapsulated into PLLA nanofibers during the electrospinning process to enrich the biofunction of as-generated sutures. All the PLLA sutures loading without or with SRHC were found to exhibit bead-free and highly-aligned nanofiber structure.
View Article and Find Full Text PDFSuspect screening and quantitative analysis of 165 contaminants of emerging concern in water, sediments, and biota using LC-MS/MS: Ecotoxicological and human health risk assessment.
Sci Total Environ
January 2025
Federal University of Santa Catarina, Agricultural Sciences Center, Department of Food Science and Technology, Brazil. Electronic address:
This study aimed to implement a targeted multiple reaction monitoring (MRM) screening strategy using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) for the initial detection of 165 compounds of emerging concern (CECs) in water, sediment, and fish samples. Following the screening, confirmatory and quantitative analyses were conducted using analytical standards for the detected compounds. Qualitative results were confirmed using high-resolution mass spectrometry (HRMS) for those CECs without available standards.
View Article and Find Full Text PDFCYP2C19 Genotype-Guided Antiplatelet Therapy and Clinical Outcomes in Patients Undergoing a Neurointerventional Procedure.
Clin Transl Sci
January 2025
Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
In neurovascular settings, including treatment and prevention of ischemic stroke and prevention of thromboembolic complications after percutaneous neurointerventional procedures, dual antiplatelet therapy with a P2Y12 inhibitor and aspirin is the standard of care. Clopidogrel remains the most commonly prescribed P2Y12 inhibitor for neurovascular indications. However, patients carrying CYP2C19 no-function alleles have diminished capacity for inhibition of platelet reactivity due to reduced formation of clopidogrel's active metabolite.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!