AI Article Synopsis
- Head and neck cancer significantly affects the quality of life (QoL) of older patients, with this study evaluating the impact of geriatric-assessment (GA)-based interventions on QoL over two years.
- The study involved 475 patients aged 65 and older, comparing those who received a GA-driven intervention to those receiving standard care, using specific QoL questionnaires for measurement.
- Results showed improvements in QoL scores overall, but no major differences between the intervention and control groups; most patients in the intervention group did not complete the full treatment, highlighting the need for better healthcare models tailored to patients' needs.
Article Abstract
Unlabelled: Due to the location and toxicity of treatments, head and neck cancer (HNC) has a major impact on quality of life (QoL). Objective: to assess the effects of geriatric-assessment (GA)-driven interventions on QoL over 2 years in older adults with HNC.EGeSOR was a randomized study of HNC patients aged ≥65, receiving a pretreatment GA, a geriatric intervention and follow-up (intervention) or standard of care (control). The primary endpoint was QoL score using the European Organisation for Research and Treatment of Cancer's (EORTC QLQ-C30) and HNC (QLQ-HN35) QoL questionnaires over 24 months.In total, 475 patients were included (median age: 75.3; women: 31%; oral cancer: 44%). QoL scores improved over 24 months with various trajectories, without significant differences between the groups. A total of 74% of patients (interventional group) did not receive the complete intervention. Cancer characteristics, functional status, and risk of frailty were associated with change in the Global Health Status QoL score.There is a need to develop an alternative model of implementation such as patient-centered health-care pathways.
Trial Registration: NCT02025062.
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| http://dx.doi.org/10.1093/jnci/djae027 | DOI Listing |
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