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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10850559PMC
http://dx.doi.org/10.3389/fmicb.2024.1370330DOI Listing

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Article Synopsis
  • The study focuses on the Mycobacterium tuberculosis Beijing 14717-15-cluster, which is a multidrug-resistant and hypervirulent strain found mainly in the Far Eastern region of Russia.
  • Researchers collected and analyzed M. tuberculosis DNA from worldwide locations between 1996 and 2020, developing a PCR assay to identify specific mutations related to this deadly strain.
  • Phylogenomic analysis confirmed the strain's prevalence in Asian Russia and highlighted unique mutations that could enhance its pathogenicity, suggesting the need for further research on these mutations' biological effects.
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