The synthesis and crystallographic analysis of the title compound, CHNOS, are reported. The compound crystallizes in the monoclinic space group 2/, revealing characteristic bond lengths and angles typical of thio-semicarbazone groups. The supra-molecular organization primarily arises from hydrogen bonding and π-π stacking inter-actions, leading to distinctive dimeric formations.
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http://dx.doi.org/10.1107/S2056989024000033 | DOI Listing |
Org Lett
July 2013
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyotodaigaku-Katsura, Nishikyo, Kyoto 615-8510, Japan.
A novel method for the asymmetric synthesis of 2-substituted indolines, employing bifunctional amino(thio)urea catalysts, was developed. The reaction proceeded via an intramolecular aza-Michael addition mediated by activation through hydrogen bonding. The catalytic process was shown to be highly versatile and applicable to a wide range of substrates due to the flexible catalytic mechanism utilizing a noncovalent interaction.
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