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Deciphering the colostral-immunity transfer: from mammary gland to neonates small intestine.
Vet Res Commun
January 2025
Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan, China.
Colostrum, the initial mammary secretion produced by various mammals following birth, is a conduit for maternal immunity transfer in diverse mammalian species. Concurrently, many cellular processes are occurring in the neonatal small intestine to prepare it to receive molecular signals from a superfood essential for the neonate's health and development. During the prepartum colostrum secretion, the newborn intestine undergoes transient alterations in the intestinal barrier, primarily regulating immunoglobulin absorption.
View Article and Find Full Text PDFDietary Habits of Pregnant Women in Spain: The Role of Nutrition Education in Midwife Consultations.
Nutrients
December 2024
Área de Nutrición y Bromatología, Facultad de Ciencias, Universidad de Burgos, Plaza Misael Bañuelos s/n, 09001 Burgos, Spain.
Correct nutrition during pregnancy is key to guaranteeing success at this stage of a woman's life, and nutritional education is the fundamental tool for achieving this. Studies carried out in different countries indicate that pregnant women do not comply with dietary and nutritional recommendations. Given the lack of evidence available in Spain and the importance of this knowledge to be able to assess the need for nutritional intervention in this group, the aim of this study focused on the current status of the issue in Spain: the quality of the diet of Spanish pregnant women and its conditioning factors.
View Article and Find Full Text PDFExpert view: Paul Coulthard.
Br Dent J
January 2025
Professor of Oral & Maxillofacial Surgery, Queen Mary University of London, UK; Honorary Professor of Oral & Maxillofacial Surgery, The University of Jordan, Jordan; The Bloomsbury Trust, London, UK.
Challenges in clinical translation of cardiac magnetic resonance imaging radiomics in non-ischemic cardiomyopathy: a narrative review.
Cardiovasc Diagn Ther
December 2024
The First Affiliated Hospital, Department of Cardiology, Hengyang Medical School, University of South China, Hengyang, China.
Background And Objective: Radiomics is an emerging technology that facilitates the quantitative analysis of multi-modal cardiac magnetic resonance imaging (MRI). This study aims to introduce a standardized workflow for applying radiomics to non-ischemic cardiomyopathies, enabling clinicians to comprehensively understand and implement this technology in clinical practice.
Methods: A computerized literature search (up to August 1, 2024) was conducted using PubMed to identify relevant studies on the roles and workflows of radiomics in non-ischemic cardiomyopathy.
Toward expert-level medical question answering with large language models.
Nat Med
January 2025
Google Research, Mountain View, CA, USA.
Large language models (LLMs) have shown promise in medical question answering, with Med-PaLM being the first to exceed a 'passing' score in United States Medical Licensing Examination style questions. However, challenges remain in long-form medical question answering and handling real-world workflows. Here, we present Med-PaLM 2, which bridges these gaps with a combination of base LLM improvements, medical domain fine-tuning and new strategies for improving reasoning and grounding through ensemble refinement and chain of retrieval.
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