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http://dx.doi.org/10.1186/s40168-024-01767-3 | DOI Listing |
Ophthalmic Physiol Opt
January 2025
Elite School of Optometry, Medical Research Foundation, Chennai, India.
Purpose: To investigate changes in fluid reservoir turbidity parameters over time and its influence on visual performance in eyes with ocular surface disorders (OSD) wearing scleral contact lenses (SL).
Methods: Thirteen eyes with OSD were assessed for corrected distance visual acuity, contrast sensitivity (CS) and fluid reservoir turbidity using anterior segment optical coherence tomography at baseline, after 5 min and 0.5, 1, 2, 3 and 4 h of SL wear on day 1 and after 1 month.
Sci Rep
January 2025
Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, Japan.
We developed an AI system capable of automatically classifying anterior eye images as either normal or indicative of corneal diseases. This study aims to investigate the influence of AI's misleading guidance on ophthalmologists' responses. This cross-sectional study included 30 cases each of infectious and immunological keratitis.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse, 3010, Bern, Switzerland.
To describe the management and clinical course of 12 cases of pseudophakic aqueous misdirection syndrome (AMS). Twelve eyes of 12 Patients diagnosed with pseudophakic AMS between 2021 and 2022 were included. Best-corrected visual acuity, refraction, intraocular pressure (IOP), anti-glaucomatous medication, spectral domain ocular coherence tomography (SD-OCT) and postoperative complications were evaluated.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia. Electronic address:
Introduction: Implantable collamer lens (ICL) is a posterior chamber phakic intraocular lens. It is usually indicated for high refractive error correction that cannot be treated by laser vision correction due to physical limitations.
Case Presentation: 39 years old male with a past ocular history of keratoconus underwent astigmatic keratotomy followed by crosslinking in both eyes a couple of years later due to signs of corneal ectasia progression.
JAMA Ophthalmol
January 2025
Xiamen Eye Center of Xiamen University, Xiamen, Fujian, China.
Importance: Bietti crystalline dystrophy (BCD) is a severe genetic retinopathy caused by variants in the CYP4V2 gene. Currently, there is no approved treatment for BCD.
Objective: To evaluate safety and vision outcomes following gene therapy with adeno-associated virus (AAV) encoding CYP4V2 (rAAV-hCYP4V2, NGGT001 [Next Generation Gene Therapeutics]).
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