Deep learning recently achieved advancement in the segmentation of medical images. In this regard, U-Net is the most predominant deep neural network, and its architecture is the most prevalent in the medical imaging society. Experiments conducted on difficult datasets directed us to the conclusion that the traditional U-Net framework appears to be deficient in certain respects, despite its overall excellence in segmenting multimodal medical images. Therefore, we propose several modifications to the existing cutting-edge U-Net model. The technical approach involves applying a Multi-Dimensional U-Convolutional Neural Network to achieve accurate segmentation of multimodal biomedical images, enhancing precision and comprehensiveness in identifying and analyzing structures across diverse imaging modalities. As a result of the enhancements, we propose a novel framework called Multi-Dimensional U-Convolutional Neural Network (MDU-CNN) as a potential successor to the U-Net framework. On a large set of multimodal medical images, we compared our proposed framework, MDU-CNN, to the classical U-Net. There have been small changes in the case of perfect images, and a huge improvement is obtained in the case of difficult images. We tested our model on five distinct datasets, each of which presented unique challenges, and found that it has obtained a better performance of 1.32%, 5.19%, 4.50%, 10.23% and 0.87%, respectively.
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http://dx.doi.org/10.1186/s12880-024-01197-5 | DOI Listing |
Ying Yong Sheng Tai Xue Bao
October 2024
Shenyang Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China.
Quantitative evaluation of urban ecological carrying capacity is a critical foundation for measuring urban sustainable development in the new era. This review would enrich the concept and connotation of urban ecological carrying capacity by sorting out its components and characteristics. We categorized the methods for quantifying urban ecological carrying capacity into static evaluation methods, including ecological footprint method, comprehensive evaluation method, state space method, net primary productivity method, and carbon-oxygen balance method, as well as dynamic simulation prediction methods, including system dynamics models, BP neural network prediction models, and grey prediction models.
View Article and Find Full Text PDFScand J Med Sci Sports
January 2025
School of Physical Education, Shanghai University of Sport, Shanghai, China.
Long-term training enables professional athletes to develop concentrated and efficient neural network organizations for specific tasks. This study used functional near-infrared spectroscopy to investigate task performance, brain functional characteristics, and their relationships in footballers during sport-specific motor-cognitive processes. Twenty-four footballers (athlete group, with 18 remaining of good signal quality) and 20 non-footballers (control group, with 16 remaining) completed four tasks: a single task (trigger buttons corresponding to the appearance direction of teammates with kicking actions), an N-back direction task, a dual task, and an N-back digit task.
View Article and Find Full Text PDFPhysiol Plant
December 2024
Laboratory of Tumor Targeted and Immune Therapy, Clinical Research Center for Breast, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China.
As an important source of pollution in the papermaking process, the presence of lignin in poplar can seriously affect the quality and process of pulping. During lignin synthesis, Caffeoyl-CoA-O methyltransferase (CCoAOMT), as a specialized catalytic transferase, can effectively regulate the methylation of caffeoyl-coenzyme A (CCoA) to feruloyl-coenzyme A. Targeting CCoAOMT, this study investigated the substrate recognition mechanism and the possible reaction mechanism, the key residues of lignin binding were mutated and the lignin content was validated by deep convolutional neural-network model based on genome-wide prediction (DCNGP).
View Article and Find Full Text PDFBrief Bioinform
November 2024
Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning, Central China Normal University, Wuhan 430079, China.
Identifying phage-host interactions (PHIs) is a crucial step in developing phage therapy, which is the promising solution to addressing the issue of antibiotic resistance in superbugs. However, the lifestyle of phages, which strongly depends on their host for life activities, limits their cultivability, making the study of predicting PHIs time-consuming and labor-intensive for traditional wet lab experiments. Although many deep learning (DL) approaches have been applied to PHIs prediction, most DL methods are predominantly based on sequence information, failing to comprehensively model the intricate relationships within PHIs.
View Article and Find Full Text PDFProc (IEEE Int Conf Healthc Inform)
June 2024
College of Medicine, University of Florida, Gainesville, FL, USA.
Multivariate clinical time series data, such as those contained in Electronic Health Records (EHR), often exhibit high levels of irregularity, notably, many missing values and varying time intervals. Existing methods usually construct deep neural network architectures that combine recurrent neural networks and time decay mechanisms to model variable correlations, impute missing values, and capture the impact of varying time intervals. The complete data matrices thus obtained from the imputation task are used for downstream risk prediction tasks.
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