AI Article Synopsis
- - Acute renal failure (ARF) is a common issue in hospitals, impacting 20% of patients, and is especially prevalent in the elderly due to age-related kidney function changes.
- - Aging kidneys struggle with maintaining fluid and sodium balance, making seniors more susceptible to chronic kidney disease and other illnesses like diabetes and hypertension.
- - Elderly patients are at higher risk for specific types of acute kidney injury (AKI), including iatrogenic AKI from multiple medications, functional AKI from fluid balance disruptions, and obstructive AKI due to urological problems.
Article Abstract
Acute renal failure (ARF) is a frequent medical problem, affecting 20% of hospitalized patients. Aging leads to functional changes in the kidney, disruptions to hydrosodium homeostasis, and is associated with a higher prevalence of chronic kidney disease due to the impact of numerous chronic illnesses (diabetes, arterial hypertension, benign prostatic hypertrophy, etc.). All these age-related impairments hamper the kidney's ability to adapt to acute events. While elderly subjects can develop all types of AKI, they are particularly at risk of iatrogenic AKI due to polymedication, functional AKI due to a change in their ability to maintain hydrosodium homeostasis, and obstructive AKI linked to urological pathologies.
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| http://dx.doi.org/10.1016/j.sger.2023.12.005 | DOI Listing |
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