AI Article Synopsis
- The non-ciliated bronchiolar cell, known as the "club cell," plays a crucial role in the airway epithelium, primarily located in the bronchioles of humans and found prominently in rodents.
- Club cells serve multiple functions, acting as regulatory cells in lung inflammation and as stem cells for lung epithelial regeneration.
- This review aims to explore club cell structure and function under normal and disease conditions to enhance the understanding of their significance in the respiratory system.
Article Abstract
The non-ciliated bronchiolar cell, also referred to as "club cell", serves as a significant multifunctional component of the airway epithelium. While the club cell is a prominent epithelial type found in rodents, it is restricted to the bronchioles in humans. Despite these differences, the club cell's importance remains undisputed in both species due to its multifunctionality as a regulatory cell in lung inflammation and a stem cell in lung epithelial regeneration. The objective of this review is to examine different aspects of club cell morphology and physiology in the lung epithelium, under both normal and pathological conditions, to provide a comprehensive understanding of its importance in the respiratory system.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.14670/HH-18-713 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!