AI Article Synopsis
- A Ukrainian patient had a severe bone infection called osteomyelitis caused by super-strong bacteria that don't respond to many medicines.
- The doctors treated the infection successfully using a medicine called cefiderocol while the patient was able to continue their care at home.
- Using cefiderocol in this way showed that it can be a safe and good choice for treating tough infections, but they also need to think about how long to use it due to effects on iron levels in the body.
Article Abstract
Objectives: Post-traumatic osteomyelitis attributed to metallo-β-lactamase (MBL)-producing Gram-negative bacteria presents a challenging clinical scenario. Cefiderocol emerges as a viable treatment option within the limited therapeutic options available.
Patient/case Description: In this brief report, we present a case of a Ukrainian patient with osteomyelitis caused by multi-drug resistant , which was successfully treated with cefiderocol, facilitated in part by outpatient parenteral antibiotic therapy (OPAT).
Results And Discussion: Administration of Cefiderocol via OPAT can present a safe and effective option for treatment of post-traumatic osteomyelitis with multi-drug resistant A possible effect on iron homeostasis of extended treatment duration with cefiderocol may be taken into consideration.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10848891 | PMC |
| http://dx.doi.org/10.1093/jacamr/dlae015 | DOI Listing |
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