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Microprolactinoma Growth During Pregnancy With Pituitary Tumor Apoplexy: Case Report and Review of the Literature.
Case Rep Endocrinol
January 2025
Unidad Académica de Endocrinología y Metabolismo, Hospital de Clínicas "Dr. Manuel Quíntela", Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
Prolactinomas are the most prevalent subtype of pituitary adenomas and represent one of the leading etiological factors responsible for amenorrhea and infertility in women. The primary therapeutic approach entails the use of dopamine agonists, which effectively restore fertility. In cases of microprolactinomas, the likelihood of experiencing a symptomatic enlargement of the tumor during pregnancy is exceptionally low, estimated at a mere 2.
View Article and Find Full Text PDFDisease activity and maternal-fetal outcomes in pregnant women with prolactinoma: A systematic review and meta-analysis.
J Clin Endocrinol Metab
November 2024
Department of Internal Medicine, São Paulo State University (UNESP), Medical School, Botucatu, São Paulo, Brazil.
Context: Women with prolactinoma are usually infertile, but can conceive after surgery or treatment with dopamine agonists (DA).
Objective: To evaluate the impact of pregnancy in prolactinoma's natural course and in maternal-fetal outcomes.
Data Sources: MEDLINE, EMBASE, LILACS, and CENTRAL.
Elucidating Clinical Queries for Tailored Therapy in Patients with Prolactinoma.
Endocrinol Metab (Seoul)
December 2024
Division of Endocrinology, Department of Internal Medicine, Institute of Endocrine Research, Yonsei University College of Medicine, Seoul, Korea.
Article Synopsis
- * While medication effectively reduces tumor size and hormone levels, issues such as treatment duration and side effects can impact patient adherence.
- * Recent advancements in surgical techniques and precision medicine offer opportunities for personalized treatment plans, focusing on factors like DA sensitivity, surgical suitability, and patient safety, especially during pregnancy and breastfeeding.
Prolactinomas: Preconception and During Pregnancy.
Endocrinol Metab Clin North Am
September 2024
Department of Medicine, Division of Endocrinology and Molecular Medicine, Medical College of Wisconsin, HUB for Collaborative Medicine, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA; Department of Neurosurgery, Medical College of Wisconsin, HUB for Collaborative Medicine, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address:
Prolactinomas are a common cause of infertility in women. Medical treatment with dopamine agonists (DAs) has an excellent efficacy at restoring fertility and a reassuring safety profile in early pregnancy. Surgical treatment before conception is required in some cases of large macroadenomas and incomplete treatment response.
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