Microfluidic paper-based analytical device with a preconcentration system for the measurement of anionic surfactants using an optode detector.

The paper discusses the development of a low-cost, simple, and sensitive on-site measurement system for anionic surfactants (AS), specifically sodium alkylbenzene sulfonate (LAS), using a microfluidic paper-based analytical device (μPAD) with an optode as a detector. The need arises due to the discharge of AS-containing wastewater into natural environments, posing risks to aquatic organisms. Traditional methods for AS measurement have drawbacks like the use of harmful solvents, time-consuming procedures, and the need for expensive equipment, prompting the exploration of alternative approaches. The μPAD incorporates a sample solution preconcentration system using filter paper modified with chitosan. The optode, a chemical sensor detecting analytes optically, is employed for AS detection. When a large volume of AS is added to a positively charged modified filter paper with chitosan, the AS is adsorbed and concentrated on the filter paper. The concentrated AS is eluted with a small volume of alkaline solution, and the eluted AS is detected by the optode in the μPAD. The μPAD with preconcentration provides improved sensitivity and a broader range of detection compared to the method without preconcentration. In the present μPAD method, linear alkylbenzenesulfonate (LAS) in the concentration range of 0.1 to 10 μmol dm was measured. The developed μPAD offers advantages such as portability, cost-effectiveness, and negligible interference from coexisting substances in environmental water samples. The μPAD method was applied for the determination of LAS in tap water and river water.