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Subtraction magnetic resonance imaging (MRI) has been reported to increase accuracy in the diagnosis of meningeal and inflammatory brain diseases in small animals. 3D T1W gradient recalled echo (GRE) techniques have been proposed as a suitable alternative to conventional spin echo sequences in imaging the canine brain. The aim of this study was to compare subtraction images and paired pre- and post-contrast 3D T1W GRE fat suppressed (FS) images in canine and feline MRI studies using clinical diagnosis as the gold standard. Paired pre- and post-contrast T1W 3D FS GRE images and individual subtraction images of 100 small animal patients were randomized and independently evaluated by 2 blinded observers. Diagnosis categories were "normal," "inflammatory," "neoplastic," and "other." Clinical diagnosis was made in the same categories and served as the gold standard. Image interpretation results were compared to the clinical diagnosis. Interobserver agreement was determined. Clinically, 41 studies were categorized as "normal," 18 as "inflammatory," 28 as "neoplastic," and 13 as "other." The agreement of the pre- and post-contrast GRE images with the gold standard was significantly higher than that of the subtraction images ( = 0.7491 vs. = 0.5924; = 0.0075). The largest sources of error were misinterpretation of "other" as "normal" and "normal" as "inflammatory." There was no significant difference between the two observers ( = 0.8820). Based on this study, subtraction images do not provide an advantage to paired pre- and post-contrast FS GRE images when evaluating the canine and feline brain.
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http://dx.doi.org/10.3389/fvets.2024.1346617 | DOI Listing |
Magn Reson Imaging
December 2024
Department of Radiology, Iwate Medical University, Yahaba, Japan.
Objective: The total examination time can be reduced if high-quality two-dimensional (2D) cine images can be collected post-contrast to minimize non-scanning time prior to late gadolinium-enhanced imaging. This study aimed to assess the equivalency of the pre-and post-contrast performance of 2D deep learning-based highly accelerated cardiac cine (DL cine) imaging by evaluating the image quality and the quantification of biventricular volumes and function in the clinical setting.
Material And Methods: Thirty patients (20 men, mean age 53.
J Neurointerv Surg
December 2024
Department of Neurology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, People's Republic of China
Background: Vessel wall MRI (VWMRI) can reveal the morphological features of intracranial artery occlusion (ICAO). This study aimed to investigate the imaging features of ICAO on VWMRI and explore their correlation with perioperative complications of endovascular recanalization for non-acute ICAO.
Methods: The study retrospectively included consecutive patients with recurrent ischemic stroke due to non-acute ICAO in the anterior circulation who underwent preoperative VWMRI evaluation and endovascular recanalization.
Acad Radiol
December 2024
Recep Tayyip Erdogan University, Department of Radiology, Rize, Turkey (M.S., E.K., M.B., F.B.C.). Electronic address:
Rationale And Objectives: Magnetic resonance imaging (MRI) is a vital tool for diagnosing neurological disorders, frequently utilising gadolinium-based contrast agents (GBCAs) to enhance resolution and specificity. However, GBCAs present certain risks, including side effects, increased costs, and repeated exposure. This study proposes an innovative approach using generative adversarial networks (GANs) for virtual contrast enhancement in brain MRI, with the aim of reducing or eliminating GBCAs, minimising associated risks, and enhancing imaging efficiency while preserving diagnostic quality.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
December 2024
Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland (A.H., W.A., A.B.,R.W., P.R.), Department of Neuroradiology, Kantonsspital Aarau, Aarau, Switzerland (P.M.), Department of Neurology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland (D.J.S.,M.G., M.R.H.), Institute of Radiology, Clinic Maennedorf, Maennedorf, Zurich, Switzerland (E.J.), Department of Neurology, RHNe, Hôpital Pourtalès, Neuchâtel, Switzerland (P.M.), Department of Rheumatology, Inselspital, University of Bern, Bern, Switzerland (L.C.) Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland (R.W., P.R.).
Imaging can help to diagnose CNS vasculitis. Yet so far, no imaging studies of CNS vasculitis at 7T are available. We share our experience of vessel wall imaging (VWI) at 7T in patients with suspected vasculitis.
View Article and Find Full Text PDFClin Imaging
December 2024
Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:
Purpose: To evaluate ferumoxytol-enhanced magnetic resonance angiography (FE-MRA) for assessment of endoleaks in patients with abdominal aortic aneurysms (AAA) and chronic kidney disease (CKD) status post endovascular aneurysm repair (EVAR).
Methods: Of 1854 patients who underwent FE-MRA at a single institution between 03/21/2014 and 08/21/2023, 21 patients with a history of AAA and CKD status post EVAR were retrospectively identified (IRB #13-001341). Multiplanar pre- and post-contrast HASTE, T1-VIBE, and high-resolution breath-held 3D MRA sequences were obtained, where a dose of 4 mg/kg of Ferumoxytol was infused over six minutes.
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