[Clinical significance and research progress of quantitative hepatitis B virus core antibody measurement].

Zhonghua Gan Zang Bing Za Zhi

Department of Infectious Disease and the Center for Liver Diseases, Peking University First Hospital, Beijing 100034, China Department of Infectious Disease, Peking University International Hospital, Beijing 102206, China Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Beijing 100044, China.

Published: January 2024

Hepatitis B virus core antibodies are specific antibodies produced after viral infection that appear early and last for a long time, and its levels in serum are measured by the double-antigen sandwich chemiluminescent microparticle immunoassay method, which has higher sensitivity and specificity, providing new clinical indicators for hepatitis B patients diagnosis, treatment, and drug withdrawal management. This article reviews the clinical significance and research progress of quantitative hepatitis B core antibody measurement and expounds on its research applications and prospects in clinical practice.

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http://dx.doi.org/10.3760/cma.j.cn501113-20231130-00255DOI Listing

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