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Development and validation of a high-throughput qPCR platform for the detection of soil-transmitted helminth infections.
PLoS Negl Trop Dis
January 2025
DeWorm3 Project, Seattle, Washington, United States of America.
Background: Historically, soil-transmitted helminth (STH) control and prevention strategies have relied on mass drug administration efforts targeting preschool and school-aged children. While these efforts have succeeded in reducing morbidity associated with STH infection, recent modeling efforts have suggested that expanding intervention to treatment of the entire community could achieve transmission interruption in some settings. Testing the feasibility of such an approach requires large-scale clinical trials, such as the DeWorm3 cluster randomized trial.
View Article and Find Full Text PDFPax Inhibition: Stressing Proximal Tubule for Successful Repair.
Am J Physiol Renal Physiol
January 2025
Division of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Machine learning paving the way for successful antegrade crossing of total chronic coronary occlusions.
Cardiovasc Diagn Ther
December 2024
Cardiology, Vascular Medicine & Pneumology, GRN Hospital Weinheim, Weinheim, Germany.
Procedural success prediction in chronic total occlusion percutaneous coronary intervention (CTO-PCI)-the rise of the machines?
Cardiovasc Diagn Ther
December 2024
Department of Cardiovascular, University Hospital Basel, Basel, Switzerland.
Selection of the apposite vacuum extractor during operative delivery: A biomechanical study.
J Chin Med Assoc
December 2024
Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.
Background: Operative delivery is a technique used during vaginal or cesarean birth to facilitate the patient's labor course through the assistance of a vacuum extractor. This method is increasingly used compared with forceps. This study aimed to investigate the forced effects of vacuum extractors comprising vacuum cups with different thicknesses on the fetal head and the vacuum extractor during vacuum-assisted delivery and to determine the optimal thickness for reducing the failure rate and minimizing neonatal and maternal morbidity.
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