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Histamine receptors and COVID-19.
Inflamm Res
January 2021
Department of Pharmacology, Medical School, National and Kapodistrian University of Athens, M. Asias 75, 11527, Athens, Greece.
Objective: Reports that the over-the-counter histamine H receptor antagonist famotidine could help treat the novel coronavirus disease (COVID-19) appeared from April 2020. We, therefore, examined reports on interactions between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and histamine receptor antagonists.
Methods: A systematic literature search was performed by 19 September 2020, and updated on 28 October 2020, in PubMed, Scopus, Cochrane Library and Google Scholar using (COVID-19 OR coronavirus OR SARS-CoV-2) AND (histamine antagonist OR famotidine OR cimetidine).
Development and validation of RP-HPLC method for simultaneous determination of cefpodoxime proxetil and H2 receptor antagonists in pharmaceutical dosage forms.
Pak J Pharm Sci
March 2019
Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi, Pakistan.
A new method on RP-HPLC is devised and validated, as per ICH guidelines, for the synchronous estimation of cefpodoxime proxetil and H2-receptor antagonits that are Cimetidine, Famotidine and Ranitidine. The method is simple, accurate, expeditious, reproducible, robust and precise. Chromatography was done on a C (250 x 4.
View Article and Find Full Text PDFUltrasensitive chemiluminescence assay for cimetidine detection based on the synergistic improving effect of Au nanoclusters and graphene quantum dots.
Luminescence
March 2019
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
A novel and sensitive chemiluminescence (CL) procedure based on the synergetic catalytic effects of gold nanoclusters (Au NCs) and graphene quantum dots (GQDs) was developed for the reliable measurement of cimetidine (CM). The initial experiments showed that the KMnO -based oxidation of alkaline rhodamine B (RhoB) generated a very weak CL emission, which was intensively enhanced in the simultaneous presence of Au NCs and GQDs. CL intermediates can be adsorbed and gathered on the surface of Au NCs, becoming more stable.
View Article and Find Full Text PDFPharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine.
Pharmaceutics
August 2018
College of Pharmacy, Dankook University, Cheon-an 31116, Korea.
A sensitive and simple chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to evaluate memantine in rat plasma. Memantine and propranolol (internal standard) in rat plasma was extracted using a methanol precipitation method. The standard curve value was 0.
View Article and Find Full Text PDFColorimetric sensor for cimetidine detection in human urine based on d-xylose protected gold nanoparticles.
Analyst
May 2018
Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 211198, China.
Herein, a simple, novel, and rapid colorimetric sensor for cimetidine (Cim) detection based on d-xylose protected gold nanoparticles (d-x@AuNPs) has been developed for the first time. The d-x@AuNPs were characterized by UV-vis, TEM and FT-IR techniques. Cimetidine causes the aggregation of d-x@AuNPs due to the formation of a strong covalent Au-N bond and electrostatic binding.
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