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| http://dx.doi.org/10.18332/tpc/182911 | DOI Listing |
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Harnessing machine learning in contemporary tobacco research.
Toxicol Rep
June 2025
Division of Molecular Medicine, Bose Institute, Kolkata 700054, India.
Machine learning (ML) has the potential to transform tobacco research and address the urgent public health crisis posed by tobacco use. Despite the well-documented health risks, cessation rates remain low. ML techniques offer innovative solutions by analyzing vast datasets to uncover patterns in smoking behavior, genetic predispositions, and effective cessation strategies.
View Article and Find Full Text PDFEpigenome-wide association study of objectively measured physical activity in peripheral blood leukocytes.
BMC Genomics
January 2025
Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
Background: Few studies have explored the association between DNA methylation and physical activity. The aim of this study was to evaluate the association of objectively measured hours of sedentary behavior (SB) and moderate physical activity (MPA) with DNA methylation. We further aimed to explore the association between SB or MPA related CpG sites and cardiometabolic traits, gene expression, and genetic variation.
View Article and Find Full Text PDFImpact of maternal and offspring smoking and breastfeeding on oesophageal cancer in adult offspring.
Nat Commun
January 2025
Department of Radiation Therapy, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China.
Numerous risk factors for oesophageal cancer are linked to lifestyle habits, but the role of early-life factors in its incidence and mortality is unclear. Using UK Biobank data, we explore the association among breastfeeding, maternal smoking, smoking in offspring, and oesophageal cancer risk in adult offspring via multivariable Cox regression. Here, we show that being breastfed, compared with not being breastfed, is associated with a lower risk of oesophageal cancer incidence (HR: 0.
View Article and Find Full Text PDFEffective interventions to prevent youth vaping behaviours: a rapid review.
BMJ Open
January 2025
School of Public Health, University of Alberta, Edmonton, Alberta, Canada
Objective: To identify effective policies and non-policy interventions preventing youth vaping behaviour initiation and assess their effectiveness by the level of intrusiveness and subpopulations.
Design: This systematic rapid review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Data Sources: Searches on MEDLINE and APA-PsycINFO for studies published between January 2019 and November 2023.
Is there a role for vitamin supplementation in pollutant-related childhood asthma?
J Allergy Clin Immunol
January 2025
Division of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA. Electronic address:
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