Study of Antimicrobial Resistance (AMR) in spp. in India.

Recent Adv Antiinfect Drug Discov

Department of Pharmacology and Pharmacy Practice, Saraswati Institute of Pharmaceutical Sciences, Near Hotel Anjali Inn, Dhanap, India.

Published: May 2024

AI Article Synopsis

  • * The article highlights that resistance to antibiotics is complicating treatment for infections, notably those caused by certain bacteria, which are a leading cause of diarrheal deaths.
  • * It emphasizes the importance of improved surveillance and the need for new treatment strategies to address the complex issue of AMR, which impacts multiple sectors including health, agriculture, and the environment.

Article Abstract

Antimicrobial agents are essential in reducing illness and mortality brought on by infectious diseases in both humans and animals. However, the therapeutic effect of antibiotics has diminished due to an increase in antimicrobial drug resistance (AMR). This article provides a retrospective analysis of AMR in infections in India, showing a rise in resistance that has contributed to a global burden. spp. are widespread and the second-leading cause of diarrheal death in people of all ages. The frequency and mortality rates of infections are decreased by antibiotic treatment. However, the growth of broad-spectrum antibiotic resistance is making it more difficult to treat many illnesses. Reduced cell permeability, efflux pumps, and the presence of enzymes that break down antibiotics are the causes of resistance. AMR is a multifaceted and cross-sectoral problem that affects humans, animals, food, and the environment. As a result, there is a growing need for new therapeutic approaches, and ongoing surveillance of spp. infections which should definitely be improved for disease prevention and management. This review emphasizes on the epidemiological data of India, and antimicrobial resistance in spp.

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Source
http://dx.doi.org/10.2174/0127724344268156231129095108DOI Listing

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