An Comparative Evaluation of Conventional and Novel Derived Herbal Disinfectant Solutions against Pathogenic Biofilm on Maxillofacial Silicones and Its Impact on Color Stability.

Aim: This study aims to assess the antimicrobial efficacy and impact on color stability of solution compared to conventional disinfectants on maxillofacial silicones.

Materials And Methods: Various solutions were evaluated, including solutions at 5 and 10%, saline (control), chlorhexidine (4%), and soap water. The substrates were MDX4-4210 silicone elastomers, and the microorganisms tested were and . The viability of microorganisms was determined through an 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) reduction assay, and color stability was measured using a spectrophotometer with X-Rite Europe software. Statistical analysis was performed using the Kruskal-Wallis test, Mann-Whitney test, and Wilcoxon Signed Rank test.

Results: Soap water demonstrated superior disinfectant action against both microorganisms, while solutions at 5 and 10% exhibited comparable antimicrobial efficacy. Chlorhexidine and 10% solution showed minimal color changes in the silicone material. In contrast, soap water and the 5% solution resulted in clinically unacceptable color alterations.

Conclusion: This study underscores the potential of as an herbal disinfectant for combating microbial biofilms on maxillofacial silicones, particularly at concentrations of 5 and 10%. The importance of maintaining color stability is emphasized, with Chlorhexidine and the 10% solution demonstrating effective preservation of esthetics. These findings suggest the viability of considering as an alternative disinfectant in clinical settings for maxillofacial silicone prostheses.

Clinical Significance: Maxillofacial silicones are vital in restoring aesthetic features for individuals with facial trauma, congenital deformities, or post-surgical interventions. Yet, biofilm-related infections jeopardize their durability and visual integrity. Clinically, signifies a potential advance in prosthodontic care, offering valuable insights for improving antimicrobial performance and aesthetic durability in maxillofacial prostheses. How to cite this article: Peter M, Kanathila H, Bembalagi M, . An Comparative Evaluation of Conventional and Novel Derived Herbal Disinfectant Solutions against Pathogenic Biofilm on Maxillofacial Silicones and Its Impact on Color Stability. J Contemp Dent Pract 2023;24(12):967-973.