Protocol for a prospective longitudinal cohort study on the effects of non-surgical weight loss on pelvic floor dysfunction.

BMJ Open

Department of Obstetrics and Gynaecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Obstetric & Gynaecologic Diseases, Beijing, China

Published: February 2024

AI Article Synopsis

  • Recent studies suggest that non-surgical weight loss and pelvic floor muscle training should be the first treatment options for obese patients dealing with urinary incontinence, but there's less research on how weight loss affects other pelvic floor dysfunctions and quality of life.
  • The "Weight Loss on Pelvic Floor Dysfunction" (WLPFD) study plans to follow 200 patients over six months, collecting data through questionnaires to evaluate the effects of weight loss on pelvic floor issues and overall quality of life.
  • The study has ethical approval from Peking Union Medical College Hospital and aims to share its findings through international journals and conferences (Trial Registration Number: NCT05987085).

Article Abstract

Introduction: Recent studies have recommended non-surgical weight loss and pelvic floor muscle training as first-line treatment for obese patients with urinary incontinence. However, limited studies are detecting the effect of weight loss on other types of pelvic floor dysfunctions (PFDs), as well as on the quality of life (QoL) and the related influencing factors.

Methods And Analysis: The "Weight Loss on Pelvic Floor Dysfunction"(WLPFD) observational study is a 6 months prospective, longitudinal real-world cohort study aiming to recruit 200 patients. Participants will be followed up three times during the study: at baseline, and at 2 and 6 months. The methodology involves recruitment and follow-up of participants, data collection through validated questionnaires, and statistical analysis to assess the impact of non-surgical weight loss on PFD and QoL.

Ethics And Dissemination: This study has been reviewed and given a favourable ethical opinion by the Peking Union Medical College Hospital ethics committee (K4278). All results from the study will be submitted to international journals and international conferences.

Trial Registration Number: NCT05987085.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10859999PMC
http://dx.doi.org/10.1136/bmjopen-2023-079143DOI Listing

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