AI Article Synopsis

  • * It covers several treatments for hypotension, including medications that act on the sympathetic nervous system such as midodrine and dihydroergotamine, as well as dopamine agonists and other agents like ephedrine and fludrocortisone, noting their unique mechanisms.
  • * The review stresses the need for better understanding of the efficacy and safety of these treatments, calling for more research to develop evidence-based guidelines to help healthcare providers make informed decisions in managing hypotension.

Article Abstract

This comprehensive literature review addresses the scarcity and limited study of hypotension treatments compared to abundant antihypertensive drugs. Hypotension, categorized as absolute, relative, or orthostatic, has diverse causes. This review explores various treatments, including drugs affecting the sympathetic nervous system, such as midodrine, dihydroergotamine, and ergotamine, which have shown efficacy in managing hypotension. Dopamine agonists/antagonists and other drugs such as ephedrine, norepinephrine, and fludrocortisone are also discussed, each with distinct mechanisms and applications. Additionally, adjunctive agents such as non-steroidal anti-inflammatory agents, caffeine, and monoamine oxidase inhibitors are reviewed for their effects on blood pressure. This review underscores the importance of understanding the efficacy and safety profiles of hypotension treatments to guide healthcare professionals in optimal drug selection and management, emphasizing the need for further research and comparative studies for evidence-based guidelines.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10837047PMC
http://dx.doi.org/10.7759/cureus.51608DOI Listing

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